Disseminated herpes simplex in newborn infants

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Disseminated Herpes Simplex in Newborn Infants.

Six cases of disseminated herpes simplex virus infection in newborn infants have been collected. The morbid anatomical and histological findings are described for the various tissues of the body. For the first time, the typical lesions were found in the lung. This and the other findings are discussed from the aetiological point of view.

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Herpes simplex virus infections in the newborn.

Herpes simplex virus (HSV) infection is a rare disease, but with serious sequelae in the newborn. Despite active treatment with high dose Acyclovir, prognosis on psychomotor development remains unfavorable. A short review of the recent literature about clinical forms, diagnosis, treatment, and disease prophylaxis is presented.

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Disseminated Herpes Simplex Virus with Fulminant Hepatitis

Disseminated herpes simplex virus (HSV) is a rare cause of acute fulminant liver failure. We hereby present a case series of three patients with acute disseminated HSV with necrotizing hepatitis successfully treated with a week course of acyclovir. Early empiric administration of acyclovir therapy while awaiting confirmatory tests is critical in this potentially lethal disease.

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Disseminated mucocutaneous herpes simplex in an atopic individual

A 30-year-old Caucasian man was referred to eye casualty by his general practitioner (GP) with a two-day history of a widespread, rapidly progressing, blistering rash with ulceration, along with red painful eyes. It started with a ‘flu-like’ illness with symptoms of malaise and arthralgia for which the patient self-medicated with ibuprofen. After one day the rash began on the shaft of the penis...

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Febrile illness in pregnancy: disseminated herpes simplex virus.

Awoman at 26 weeks of gestation presented with 2 days of nausea, vomiting, fevers, and abdominal pain. She had no recent travel or sick contacts. Her medical history was significant for gonorrhea and cholecystectomy. On physical examination her temperature was 38.5 ̊C and she had right abdominal tenderness with a normal pelvic examination and no signs of preterm labor. The nonstress test was rea...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1963

ISSN: 0021-9746

DOI: 10.1136/jcp.16.5.423